Résumé Marcotte 2020


Référence complète

Marcotte, K., Sanchez, E., Arbour, C., Brambati, S.M., Bedetti, C., Martineau, S., Descoteaux, M. et Gosselin, N. (2020). Long-term discourse outcomes and their relationship to white matter damage in moderate to severe adulthood traumatic brain injury. Brain and Language. 204. 104769. 

#SLP #discourse #TBI

RÉSUMÉ/ABSTRACT (en anglais)

Little is known about the neural correlates of communication impairments following moderate to severe traumatic brain injury (TBI). We aimed to characterize the relationship between discourse impairments in patients presenting with chronic TBI and white matter damage. We compared 15 moderate to severe chronic TBI patients (mean age, 32.1 ± 14.9 years; age range, 18-60; age range, 18-60 years old; mean time post-TBI, 21.6 ± 9.3 months) with 15 healthy controls (mean age, 30.9 ± 15.4 years; age range, 18-60 years old) using probabilistic high-angular resolution diffusion imaging-based tractography to investigate white matter fiber bundles that are known for their role in language and vulnerability to TBI. Patients with TBI showed persistent conversational discourse impairments. They exhibited lower FA when compared with controls in language-related fiber bundles and the genu of the corpus callosum, and higher RD in language-related bundles. In the TBI group, there was a positive correlation between conversational scores and FA in the left arcuate fasciculus and a negative correlation with RD, but both did not survive Bonferroni correction. These results provide evidence that persistent conversational impairments in TBI patients are associated with structural lesions in the left arcuate fasciculus.

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